Loaded Human IL-4RA-Fc on Protein A Biosensor, can bind Human IL-4 with an affinity constant of 0.99 nM as determined in BLI assay.
Loaded Human IL-4RA-Fc on Protein A Biosensor, can bind Human IL-4-His with an affinity constant of 0.99 nM as determined in BLI assay.
Measured by its ability to inhibit IL-4-dependent proliferation of TFb1 human erythroleukemic cells. The ED50 for this effect is 5-20 ng/ml.