Recombinant Human IL6 Protein (Pro29-Met212), Tag Free
Product Description
Cat
IMP-7134
Official Symbol
IL6
Product Overview
Purified recombinant protein of Human interleukin 6 (interferon, beta 2) (IL6) without tag was produced in E. coli.
Description
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]
Expression System
E. coli
Species
Human
Tag
Tag free
Form
10mM NaH2PO4, 0.15 M NaCl, pH7.2
Molecular Mass
21 kDa
Protein length
Pro29-Met212
Endotoxin
< 0.01 ng/μg protein as determined by the LAL method
Purity
> 98% as determined by Coomassie stained SDS-PAGE.
Storage
Store at -80 centigrade.
Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Concentration
lot specific
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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