Recombinant Human IL6 Protein (Pro29-Met212), Tag Free
Product Description
Cat
IMP-7138
Official Symbol
IL6
Product Overview
Recombinant protein of human Interleukin 6(IL-6) without tag was produced in E. coli.
Description
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]
Expression System
E. coli
Species
Human
Tag
Tag free
Form
Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4.
Molecular Mass
20.9 kDa
Protein length
Pro29-Met212
Endotoxin
< 0.01 ng/μg protein as determined by the LAL method
Purity
> 95% as determined by SDS-PAGE and Coomassie blue staining
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
Resuspend the protein to the desired concentration in proper buffer.
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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