Recombinant Human IL6 Protein (Val30-Met212), His-tagged
Product Description
Cat
IMP-7137
Official Symbol
IL6
Product Overview
Recombinant protein of human interleukin 6 (interferon, beta 2) (IL6), the mature form (Pro29-Met212) with C-terminal His tag was expressed in E. coli.
Description
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020]
Expression System
E. coli
Species
Human
Tag
His
Form
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Molecular Mass
20.9 kDa
Protein length
Val30-Met212
Endotoxin
< 0.1 ng/μg (1 EU/μg)
Purity
> 95% as determined by SDS-PAGE and Coomassie blue staining
Storage
Store at -80 centigrade.
Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Concentration
lot specific
SDS-PAGE
SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

Online Inquiry
Contact Info