Recombinant Human ITGAV&ITGB3 Protein, C-His-tagged
Product Description
Cat
IMP-4771
Official Symbol
ITGAV&ITGB3
Product Overview
Recombinant extracellular domain (Met1-Val992) of human ITGAV (P06756) was fused with a his tag at the C-terminus, constructed the plasmid 1; Recombinant extracellular domain (Met1-Asp718) of human ITGB3 (P05106) constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB3 heterodimer was purified.
Description
Integrin alpha-V&beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
Expression System
HEK293
Species
Human
Tag
C-His
Predicted N Terminal
Phe31&Gly27
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.
Molecular Mass
The recombinant heterodimer of human ITGAV&ITGB3 comprises 1751 (1015+736) amino acids and has a calculated molecular mass of 193.32 (112.22+81.1) KDa.
Protein length
Met1-Val992 and Met1-Asp718
Endotoxin
< 1.0 EU/μg of the protein as determined by the LAL method
Purity
> 95 % as determined by SDS-PAGE
Storage
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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