Recombinant Human ITGAX&ITGB2 Protein, C-His-tagged
Product Description
Cat
IMP-4773
Official Symbol
ITGAX&ITGB2
Product Overview
Recombinant extracellular domain (Met1-Pro1107) of human ITGAX (P20702) was expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 1; Recombinant extracellular domain (Met1-Asn700) of human ITGB2 (P05107), constructed the plasmid 2. The two plasmids were co-expressed and the heterodimer was purified.
Description
Integrin alpha-V&beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
Expression System
HEK293
Species
Human
Tag
C-His
Predicted N Terminal
Phe 20&Gln 23
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.
Molecular Mass
The recombinant heterodimer of human ITGAX&ITGB2 comprises 1859 (1140+719) amino acids and has a calculated molecular mass of 204.8 (125.62+79.18) kDa.
Protein length
Met1-Pro1107 and Met1-Asn700
Endotoxin
< 1.0 EU/μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Storage
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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