Recombinant Human JAG1 Protein (37-119), N-GST-tagged

Product Description

Cat

IMP-8075

Official Symbol

JAG1

Product Overview

Human JAG1 partial ORF ( NP_000205.1, 37 a.a.-119 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ (in vitro).

Description

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Expression System

Wheat Germ (in vitro)

Species

Human

Tag

N-GST

Form

50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Molecular Mass

34.76 kDa

Protein length

37-119

AA Sequence

LEILSMQNVNGELQNGNCCGGARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNR

Applications

ELISA; WB (Recombinant protein); Antibody Production; Protein Array

Notes

Best use within three months from the date of receipt of this protein.

Storage

Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

12.5% SDS-PAGE Stained with Coomassie Blue.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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