Recombinant Human KDR Protein (Met-Ala20-Glu764), C-DDK-tagged
Product Description
Cat
IMP-7695
Official Symbol
KDR
Product Overview
Purified recombinant protein of Human kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), residues 20-764aa, with C-terminal DDK tag, expressed in sf9.
Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
Expression System
Insect cells
Species
Human
Tag
C-DDK
Form
50mM Tris-HCl pH 8.0, 100mM glycine, 10% glycerol
Molecular Mass
83.3 kDa
Protein length
Met-Ala20-Glu764
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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