Recombinant Human KDR Protein (Met-Ala20-Glu764), C-DDK-tagged
Product Description
Cat
IMP-7695
Official Symbol
KDR
Product Overview
Purified recombinant protein of Human kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), residues 20-764aa, with C-terminal DDK tag, expressed in sf9.
Description
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
Expression System
Insect cells
Species
Human
Tag
C-DDK
Form
50mM Tris-HCl pH 8.0, 100mM glycine, 10% glycerol
Molecular Mass
83.3 kDa
Protein length
Met-Ala20-Glu764
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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