Recombinant Human KRAS Protein (full-length), N-AVI-tagged

Product Description

Cat

IMP-6903

Official Symbol

KRAS

Product Overview

Purified recombinant protein of Human v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), transcript variant b, full length, with N-terminal AVI tag, expressed in E. coli.

Description

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Expression System

E. coli

Species

Human

Tag

N-AVI

Form

50mM Tris, pH 8.0, 500mM NaCl, 10% glycerol

Molecular Mass

21.2 kDa

Protein length

Full Length

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining.

Storage

Store at -80 centigrade.
Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Concentration

> 50 μg/mL as determined by Bradford protein assay method.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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