Description
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Human LSECtin/CLEC4G is coated at 1 μg/mL, 100 μL/well, biotinylated recombinant LAG-3 Fc Chimera binds with an ED50 of 0.2-2 μg/mL.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
