Recombinant Human LEP Protein, Tag free
Product Description
Cat
IMP-8569
Official Symbol
LEP
Product Overview
Human LEP (Q6NT58) recombinant protein expressed in E. coli.
Description
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
Expression System
E. coli
Species
Human
Tag
Tag free
Form
Lyophilized, No additive
Molecular Mass
16 kDa
AA Sequence
MVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC
Endotoxin
< 0.1 EU/μg
Applications
Functional Study; SDS-PAGE
Storage
Store at -20 centigrade on dry atmosphere. After reconstitution with sterilized water, store at -20 or -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

1 μg/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue Lane 1: non-reducing conditions Lane 2: reducing conditions

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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