Recombinant Human MSLN Protein (Asn402-Thr581), N-His-tagged
Product Description
Cat
IMP-7749
Official Symbol
Msln
Product Overview
Purified recombinant protein of Human mesothelin (MSLN), transcript variant 2, Asn402-Thr581, with N-terminal His tag, expressed in E.coli.
Description
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Expression System
E. coli
Species
Human
Tag
N-His
Form
25mM Tris, pH 8.0, 150mM NaCl, 10% glycerol
Molecular Mass
20.3 kDa
Protein length
Asn402-Thr581
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade after receiving vials.
Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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