Recombinant Human NCR3LG1 Protein, C-hFc-tagged

Product Description

Cat

IMP-1389

Official Symbol

NCR3LG1

Product Overview

Recombinant human NCR3LG1 (NP_001189368.1) (Met1-Ser262) was expressed with the Fc region of human IgG1 at the C-terminus.

Description

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity.

Expression System

HEK293

Species

Human

Tag

C-hFc

Predicted N Terminal

Asp 25

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant human NCR3LG1 consists 476 amino acids and predicts a molecular mass of 53.4 kDa.

Protein length

Met1-Ser262

Endotoxin

< 1.0 EU/μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Bioactivity-ELISA 1

Measured by its binding ability in a functional ELISA. Immobilized human NCR3 at 10 μg/mL (100 μL/well) can bind human B7-H6, the EC50 of human B7-H6 is 20-100 ng/mL.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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