Recombinant Human NCR3LG1 Protein, C-hFc-tagged

Product Description

Cat

IMP-1389

Official Symbol

NCR3LG1

Product Overview

Recombinant human NCR3LG1 (NP_001189368.1) (Met1-Ser262) was expressed with the Fc region of human IgG1 at the C-terminus.

Description

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity.

Expression System

HEK293

Species

Human

Tag

C-hFc

Predicted N Terminal

Asp 25

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant human NCR3LG1 consists 476 amino acids and predicts a molecular mass of 53.4 kDa.

Protein length

Met1-Ser262

Endotoxin

< 1.0 EU/μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Bioactivity-ELISA 1

Measured by its binding ability in a functional ELISA. Immobilized human NCR3 at 10 μg/mL (100 μL/well) can bind human B7-H6, the EC50 of human B7-H6 is 20-100 ng/mL.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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