Recombinant Human PDCD1 Protein (21-170), C-hIgG-tagged

Product Description

Cat

IMP-8715

Official Symbol

PDCD1

Product Overview

Human PDCD1 (NP_005009.2, 21 a.a.- 170 a.a.) partial recombinant protein with C-terminal hIgG tag expressed in HEK293 cells.

Description

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Expression System

HEK293

Species

Human

Tag

C-hIgG

Form

Liquid, In PBS, pH 7.4 (10% glycerol).

Molecular Mass

42.9 kDa

Protein length

21-170

Endotoxin

< 1 EU/μg of protein (determined by LAL method).

Purity

> 95% by SDS-PAGE

Applications

SDS-PAGE

Storage

Store at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Bioactivity-ELISA 1

PDCD1 (Human) Recombinant Protein is coated at 5 μg/mL (100 μL/well) can bind Human PD-L1/B7-H1 in a Functional ELISA assay.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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