Recombinant Human PDCD1 Protein (21-170), C-hIgG-tagged

Product Description

Cat

IMP-8715

Official Symbol

PDCD1

Product Overview

Human PDCD1 (NP_005009.2, 21 a.a.- 170 a.a.) partial recombinant protein with C-terminal hIgG tag expressed in HEK293 cells.

Description

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Expression System

HEK293

Species

Human

Tag

C-hIgG

Form

Liquid, In PBS, pH 7.4 (10% glycerol).

Molecular Mass

42.9 kDa

Protein length

21-170

Endotoxin

< 1 EU/μg of protein (determined by LAL method).

Purity

> 95% by SDS-PAGE

Applications

SDS-PAGE

Storage

Store at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Aliquot to avoid repeated freezing and thawing.

SDS-PAGE

3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Bioactivity-ELISA 1

PDCD1 (Human) Recombinant Protein is coated at 5 μg/mL (100 μL/well) can bind Human PD-L1/B7-H1 in a Functional ELISA assay.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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