Recombinant Human PDCD1 Protein (25-168), C-Fc/6×His-tagged
Product Description
Cat
IMP-8716
Official Symbol
PDCD1
Product Overview
Human PDCD1 (NP_005009.2, 25 a.a.-168 a.a.) partial recombinant protein with Fc, 6xHis tag at C-terminal expressed in HEK293 cells.
Description
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Expression System
HEK293
Species
Human
Tag
C-Fc/6×His
Form
Lyophilized from 0.22 μM filtered solution of PBS, pH 7.4.
Protein length
25-168
Endotoxin
< 0.1 EU/μg of the protein by LAL method.
Purity
> 97% by SDS-PAGE
Applications
SDS-PAGE
Storage
Store the lyophilized protein at -20 to -80 centigrade for long term. After reconstitution with a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20 centigrade for 3 months, at 2-8 centigrade for up to 1 week. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

SDS-PAGE Stained with Coomassie Blue, This protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 60-70 kDa.

Bioactivity-ELISA 1
Result of bioactivity analysis

Immobilized PDCD1 (Human) Recombinant Protein at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-L1 with a linear range of 0.3-1.3 μg/mL.

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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