Recombinant Human PDCD1 Protein (25-168), C-Fc/6×His-tagged
Product Description
Cat
IMP-8716
Official Symbol
PDCD1
Product Overview
Human PDCD1 (NP_005009.2, 25 a.a.-168 a.a.) partial recombinant protein with Fc, 6xHis tag at C-terminal expressed in HEK293 cells.
Description
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Expression System
HEK293
Species
Human
Tag
C-Fc/6×His
Form
Lyophilized from 0.22 μM filtered solution of PBS, pH 7.4.
Protein length
25-168
Endotoxin
< 0.1 EU/μg of the protein by LAL method.
Purity
> 97% by SDS-PAGE
Applications
SDS-PAGE
Storage
Store the lyophilized protein at -20 to -80 centigrade for long term. After reconstitution with a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20 centigrade for 3 months, at 2-8 centigrade for up to 1 week. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

SDS-PAGE Stained with Coomassie Blue, This protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 60-70 kDa.

Bioactivity-ELISA 1
Result of bioactivity analysis

Immobilized PDCD1 (Human) Recombinant Protein at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-L1 with a linear range of 0.3-1.3 μg/mL.

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry
Contact Info