Recombinant Human PDCD1 Protein (33-145), N-His/Flag/StrepII-tagged
Product Description
Cat
IMP-8722
Official Symbol
PDCD1
Product Overview
Purified PDCD1 (AAH74740.1, 33 a.a.-145 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus was expressed in human HEK293H cells.
Description
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Expression System
HEK293H
Species
Human
Tag
N-His/Flag/StrepII
Form
Liquid, 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
Molecular Mass
17.71 kDa
Protein length
33-145
AA Sequence
NPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAAFPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVT
Applications
WB; ELISA; SDS-PAGE; Protein Interaction
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration
≥ 10 μg/mL
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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