Recombinant Human PDGFRA Protein (550-1089), N-GST-tagged
Product Description
Cat
IMP-8730
Official Symbol
PDGFRA
Product Overview
Human PDGFRA (NP_006197.1, 550 a.a.-1089 a.a.) partial recombinant protein with GST-tag at N-terminal using baculovirus expression system.
Description
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Expression System
Viruses
Species
Human
Tag
N-GST
Form
Liquid, 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Protein length
550-1089
Purity
0.92
Applications
Functional Study
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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