Description
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Form
Presentation State: Purified
State: Liquid purified protein
Buffer System: 20 mM Tris 8.0, 0.20 mM NaCl, 0.5 mM DTT, 10% glycerol
