Product Overview
Purified recombinant protein of Human R-spondin 3 homolog (Xenopus laevis) (RSPO3), Gln22-End, with N-terminal His tag, expressed in E. coli.
Description
This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development. [provided by RefSeq, Jul 2013]
