Product Overview
Purified recombinant protein of Human R-spondin family, member 4 (RSPO4), transcript variant 1, Leu20-End, with N-terminal His tag, expressed in E.coli.
Description
This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]