Recombinant Human TEK Protein (771-1124), GST-tagged
Product Description
Cat
IMP-8916
Official Symbol
TEK
Product Overview
Human TEK (NM_000459, 771 a.a.-1124 a.a.) partial recombinant protein with GST tag was expressed in Sf9 cells.
Description
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Expression System
Insect cells
Species
Human
Tag
GST
Form
Liquid, In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
Molecular Mass
66.882 kDa
Protein length
771-1124
Applications
Functional Study; SDS-PAGE
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration
0.672 μg/μL
SDS-PAGE
Quality Control Testing

2 μg/lane SDS-PAGE Stained with Coomassie Blue

Bioactivity-ELISA 1
Result of activity analysis

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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