Recombinant Human TGFB1 Protein, Tag free

Product Description

Cat

IMP-8926

Official Symbol

TGFB1

Product Overview

Human TGFB1 (P01137) recombinant protein expressed in HEK293 cells.

Description

TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2, and TGFB3 all function through the same receptor signaling systems.

Expression System

HEK293

Species

Human

Tag

Tag free

Form

Lyophilized with 10 mM HCl, 50 μg BSA per mg/mL of protein.

Molecular Mass

25 kDa

AA Sequence

ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS

Endotoxin

< 0.1 EU/μg

Applications

Functional Study; SDS-PAGE

Storage

Store at -20 centigrade on dry atmosphere. After reconstitution with sterilized water, store at -20 centigrade. Aliquot to avoid repeated freezing and thawing.

Bioactivity-ELISA 1

Serial dilutions of Human TGFB1 (starting at 10 ng/mL) were added to HT-2 cultured with IL-4. Cell proliferation was measured and the linear portion of the curve was us used to calculate the ED50.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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