Recombinant Human TGFBR3 Protein, C-His-tagged

Product Description

Cat

IMP-8943

Official Symbol

TGFBR3

Product Overview

Human TGFBR3 recombinant protein with polyhistidine tag at the C-terminus expressed in E. coli.

Description

Transforming growth factor (TGF)-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. Three TGF-beta forms are encoded by separate genes: TGFB1, TGFB2, and TGFB3. The diverse effects of TGF-beta are mediated by the TGF-beta receptors and cell surface-binding proteins. Three TGF-beta receptors exist: type I (TGFBR1), type II (TFGBR2), and type III (TGFBR3). TGFBR3 is a glycoprotein that binds TGFB and exists in both a membrane-bound and a soluble form.

Expression System

E. coli

Species

Human

Tag

C-His

Form

Lyophilized from a solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. Reconstitute the lyophilized powder in ddH2O to 100 μg/mL. In some experiments, it recommends to add 10 mM HCl when reconstitute lyophilized protein.

AA Sequence

MALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS with polyhistidine tag at the C-terminus.

Endotoxin

< 0.1 EU/μg of protein by the LAL method.

Purity

> 98% by SDS-PAGE

Applications

Functional Study; SDS-PAGE

Storage

Lyophilized protein should be stored at -20 centigrade. Protein aliquots should be stored at-20 to -80 centigrade. Avoid repeated freeze/thaw cycles.

SDS-PAGE

SDS-PAGE Stained with Coomassie Blue. SDS-PAGE analysis of TGFBR3 (Human) Recombinant Protein.

Bioactivity-ELISA 1

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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