Recombinant Human TGFBR3 Protein (Gly21-Asp781)
Product Description
Cat
IMP-9729
Official Symbol
TGFBR3
Product Overview
Recombinant human TGF-beta RIII protein (Gly21-Asp781) without tag was expressed in Mouse myeloma cell line.
Description
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Expression System
Mouse myeloma cell line
Species
Human
Tag
Tag Free
Predicted N Terminal
Gly21
Form
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Molecular Mass
Predicted Molecular Mass: 84 kDa
SDS-PAGE: 100-190 kDa, reducing conditions
Protein length
Gly21-Asp781
Bio-activity
Measured by its ability to inhibit TGF-beta 2 activity on HT-2 mouse T cells. The ED50 for this effect is 20-50 ng/mL in the presence of 0.4 ng/mL of rhTGF-beta 2.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 200 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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