Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Storage
Store at -20 centigrade on dry atmosphere for at least 6 months. After reconstitution with 50 uL sterile deionized water, store at -20 centigrade or lower. Aliquot to avoid repeated freezing and thawing.
