Product Overview
Recombinant human TRAILR1/TNFRSF10A protein (Ala109-Asn239) & (Thr110-Asn239) with a human IgG1 (Pro100-Lys330) Fc tag and 6×His tag at C-terminus was expressed in Spodoptera frugiperda, Sf 21 (baculovirus) cells.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
