Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Storage
Stored at -20 to -80 centigrade. After reconstitution with sterile water not less than 0.1 mg/mL, store at -20 to -80 centigrade for 6 months, store at 4 centigrade for 1 month. Aliquot to avoid repeated freezing and thawing.
