Recombinant Human TNFRSF11A Protein, Tag free
Product Description
Cat
IMP-9129
Official Symbol
TNFRSF11A
Product Overview
Human TNFRSF11A (Q9Y6Q6) recombinant protein expressed in E. coli.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells.
Expression System
E. coli
Species
Human
Tag
Tag free
Form
Lyophilized from PBS, pH 7.2.
Molecular Mass
19 kDa
AA Sequence
MQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARK
Endotoxin
≤ 1 EUs/μg (LAL gel clot method)
Purity
> 95%
Applications
WB; Functional Study
Storage
Stored at -20 to -80 centigrade. After reconstitution with sterile water not less than 0.1 mg/mL, store at -20 to -80 centigrade for 6 months, store at 4 centigrade for 1 month. Aliquot to avoid repeated freezing and thawing.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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