Product Overview
Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), with C-terminal DDK/His tag, expressed in human cells.
Description
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]