Recombinant Human TNFRSF14 Protein (Pro37-Val202), C-Fc-tagged, Alexa Fluor 488 Conjugated

Product Description

Cat

IMP-10011

Official Symbol

TNFRSF14

Product Overview

Alexa Fluor 488 conjugated recombinant human HVEM/TNFRSF14 protein (Pro37-Val202) with with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in human embryonic kidney cell.
Labeled with Alexa Fluor 488 via amines
Excitation Wavelength: 488 nm
Emission Wavelength: 515-545 nm

Description

This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.

Expression System

HEK293

Species

Human

Tag

C-Fc

Predicted N Terminal

Pro37

Form

Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Conjugate

Alexa Fluor 488

Molecular Mass

Predicted Molecular Mass: 44 kDa
SDS-PAGE: 55-75 kDa, under reducing conditions.

Protein length

Pro37-Val202

Bio-activity

Measured by flow cytometry for its ability to bind anti-humanHVEM/TNFRSF14 Antibody conjugated beads. The concentration of Recombinant Human HVEM/TNFRSF14 Fc Chimera Alexa Fluor 488 that produces 50% of the binding response is 15.0-150 ng/mL.

Endotoxin

<1.0 EU/μg of the protein by the LAL method.

Purity

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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