Recombinant Human TNFRSF17 Protein (Met1-Ala54), C-Fc-tagged, Alexa Fluor 647 Conjugated

Product Description

Cat

IMP-10024

Official Symbol

TNFRSF17

Product Overview

Alexa Fluor 647 conjugated recombinant human BCMA/TNFRSF17 protein (Met1-Ala54) with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line.
Labeled with Alexa Fluor 647
Excitation Wavelength: 650 nm
Emission Wavelength: 668 nm

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Expression System

Mouse myeloma cell line

Species

Human

Tag

C-Fc

Predicted N Terminal

Met1

Form

Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Conjugate

Alexa Fluor 647

Molecular Mass

Predicted Molecular Mass: 32 kDa (monomer)
SDS-PAGE: 35-45 kDa, reducing conditions

Protein length

Met1-Ala54

Bio-activity

Measured by flow cytometry for its ability to bind anti-Human BCMA/TNFRSF17 Monoclonal Antibody conjugated beads. The concentration of Recombinant human BCMA/TNFRSF17 Chimera Alexa Fluor 647 that produces 50% of the binding response is 0.5-5.0 ng/mL.

Endotoxin

<1.0 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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