Recombinant Human TNFRSF17 Protein (Met1-Ala54), C-Fc-tagged, Alexa Fluor 647 Conjugated

Product Description

Cat

IMP-10024

Official Symbol

TNFRSF17

Product Overview

Alexa Fluor 647 conjugated recombinant human BCMA/TNFRSF17 protein (Met1-Ala54) with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line.
Labeled with Alexa Fluor 647
Excitation Wavelength: 650 nm
Emission Wavelength: 668 nm

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Expression System

Mouse myeloma cell line

Species

Human

Tag

C-Fc

Predicted N Terminal

Met1

Form

Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Conjugate

Alexa Fluor 647

Molecular Mass

Predicted Molecular Mass: 32 kDa (monomer)
SDS-PAGE: 35-45 kDa, reducing conditions

Protein length

Met1-Ala54

Bio-activity

Measured by flow cytometry for its ability to bind anti-Human BCMA/TNFRSF17 Monoclonal Antibody conjugated beads. The concentration of Recombinant human BCMA/TNFRSF17 Chimera Alexa Fluor 647 that produces 50% of the binding response is 0.5-5.0 ng/mL.

Endotoxin

<1.0 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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