Recombinant Human TNFRSF1A Protein (22-211), His-tagged
Product Description
Cat
IMP-8956
Official Symbol
TNFRSF1A
Product Overview
Human TNFRSF1A (NP_001056, 22 a.a.-211 a.a ) partial recombinant protein with His tag was expressed in E. coli.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Expression System
E. coli
Species
Human
Tag
His
Form
Liquid, In 20 mM Tris-HCl buffer, pH 8.0 (10% glycerol).
Molecular Mass
23.6 kDa
Protein length
22-211
AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTT
Purity
> 85% by SDS-PAGE
Applications
SDS-PAGE
Storage
Store at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Concentration
1 mg/mL
SDS-PAGE
Quality Control Testing

SDS-PAGE analysis of TNFRSF1A (Human) Recombinant Protein, 3 μg by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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