Recombinant Human TNFRSF4 Protein (Leu29-Ala216), C-hFc and 6×His-tagged
Product Description
Cat
IMP-7824
Official Symbol
TNFRSF4
Product Overview
Recombinant Human OX40 Protein with C-Human Fc (Glu99-Ala330) and 6×His was expressed in HEK293.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Expression System
HEK293
Species
Human
Tag
C-hFc and 6×His
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5-8 % trehalose is added as protectants before lyophilization.
Molecular Mass
47.2 kDa
Protein length
Leu29-Ala216
Purity
> 95%
Applications
FC
Storage
Store the lyophilized protein at -20 centigrade. After reconstitution, store the protein at -80 centigrade for 12 months. Avoid repeated freezing and thawing.
Stability: 12 months from date of despatch.
Reconstitution
Reconstitute with deionized water.
Bioactivity-FACS 1
Bioactivity

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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