Recombinant Human TNFRSF4 Protein (Leu29-Ala216), C-hFc and 6×His-tagged
Product Description
Cat
IMP-7824
Official Symbol
TNFRSF4
Product Overview
Recombinant Human OX40 Protein with C-Human Fc (Glu99-Ala330) and 6×His was expressed in HEK293.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Expression System
HEK293
Species
Human
Tag
C-hFc and 6×His
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5-8 % trehalose is added as protectants before lyophilization.
Molecular Mass
47.2 kDa
Protein length
Leu29-Ala216
Purity
> 95%
Applications
FC
Storage
Store the lyophilized protein at -20 centigrade. After reconstitution, store the protein at -80 centigrade for 12 months. Avoid repeated freezing and thawing.
Stability: 12 months from date of despatch.
Reconstitution
Reconstitute with deionized water.
Bioactivity-FACS 1
Bioactivity

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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