Recombinant Human TNFRSF8 Protein (19-379), C-His-tagged
Product Description
Cat
IMP-9244
Official Symbol
TNFRSF8
Product Overview
Human TNFRSF8 (P28908, 19 a.a.-379 a.a.) partial recombinant protein with His tag at C-terminus was expressed in HEK293 cells.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Expression System
HEK293
Species
Human
Tag
C-His
Form
Lyophilized from sterile distilled Water up to 100 μg/mL
Molecular Mass
80 kDa
Protein length
19-379
AA Sequence
FPQDRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRDDLVEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSRDDLVEKTPCAWNSSRTCECRPGMICATSATNSCARCVPYPICAAETVTKPQDMAEKDTTFEAPPLGTQPDCNPTPENGEAPASTSPTQSLLVDSQASKTLPIPTSAPVALSSTGK
Endotoxin
< 1 EU/μg of protein (determined by gel clotting method)
Purity
> 90% by SDS-PAGE
Applications
SDS-PAGE
Storage
Store at 4 to 8 centigrade for 1 week. For long term storage store at -20 to -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

2 μg protein in Reducing SDS-PAGE

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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