Recombinant Human TNFRSF8 Protein (Met-Phe19-Lys379), C-DDK-tagged
Product Description
Cat
IMP-7827
Official Symbol
TNFRSF8
Product Overview
Recombinant protein of human tumor necrosis factor receptor superfamily, member 8 (TNFRSF8), transcript variant 1, residues 19-379aa, with C-terminal DDK tag, expressed in sf9 cells.
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Expression System
Insect cells
Species
Human
Tag
C-DDK
Form
50mM Tris-HCl pH 8.0, 100mM glycine, 10% glycerol
Molecular Mass
40.4 kDa
Protein length
Met-Phe19-Lys379
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining.
Storage
Store at -80 centigrade.
Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Concentration
> 50 μg/mL as determined by microplate BCA method.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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