Recombinant Human TNFSF18 Protein, C-mFc-tagged

Product Description

Cat

IMP-1542

Official Symbol

TNFSF18

Product Overview

Recombinant human TNFSF18 (NP_005083.3) (Gln72-Ser199) was expressed with the Fc region of mouse IgG2a at the C-terminus.

Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Expression System

HEK293

Species

Human

Tag

C-mFc

Predicted N Terminal

Gln 72

Form

Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.

Molecular Mass

The recombinant human TNFSF18 consists of 361 amino acids and predicts a molecular mass of 40.9 kDa. It migrates as an approximately 45.5 kDa band in SDS-PAGE under reducing conditions.

Protein length

Gln72-Ser199

Endotoxin

< 1.0 EU/μg protein as determined by the LAL method.

Purity

> 90 % as determined by SDS-PAGE

Storage

Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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