Recombinant Human TNFSF18 Protein (Glu52-Ser177), N-HA-tagged, Alexa Fluor 647 Conjugated

Product Description

Cat

IMP-10030

Official Symbol

TNFSF18

Product Overview

Alexa Fluor 647 conjugated recombinant human GITR Ligand protein (Glu52-Ser177) with HA (YPYDVPDYA) at N-terminus was expressed in Chinese Hamster Ovary cell line.
Labeled with Alexa Fluor 647
Excitation Wavelength: 650 nm
Emission Wavelength: 668 nm

Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Expression System

CHO

Species

Human

Tag

N-HA

Predicted N Terminal

Tyr

Form

Supplied as a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Conjugate

Alexa Fluor 647

Molecular Mass

Predicted Molecular Mass: 19.6 kDa (monomer)
SDS-PAGE: 20-27 kDa, under reducing conditions.

Protein length

Glu52-Ser177

Bio-activity

Measured by flow cytometry for its ability to bind anti-human GITR Ligand/TNFSF18 antibody conjugated beads. The concentration of Recombinant Human GITR Ligand/TNFSF18 (GCN4-IZ) Alexa Fluor 647 that produces 50% of the binding response is 0.200-2.00 ng/mL.

Endotoxin

<1.0 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Storage

Protect from light. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
6 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.

SDS-PAGE

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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