Recombinant Human TNFSF4 Protein (51-183), N-His/Flag-tagged
Product Description
Cat
IMP-8990
Official Symbol
TNFSF4
Product Overview
Human TNFSF4 (P23510, 51 a.a.-183 a.a.) partial recombinant protein with His-Flag tag at N-terminus expressed in Expi293 cells.
Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Expression System
Expi293
Species
Human
Tag
N-His/Flag
Form
Lyophilized from sterile distilled Water up to 100 μg/mL
Molecular Mass
65-140 kDa
Protein length
51-183
AA Sequence
QVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL
Endotoxin
< 1 EU/μg of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Applications
Functional Study; SDS-PAGE
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

SDS-PAGE under reducing condition

Bioactivity-ELISA 1
Result of bioactivity analysis

Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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