Recombinant Human TNFSF4 Protein (51-183), N-His/Flag-tagged
Product Description
Cat
IMP-8990
Official Symbol
TNFSF4
Product Overview
Human TNFSF4 (P23510, 51 a.a.-183 a.a.) partial recombinant protein with His-Flag tag at N-terminus expressed in Expi293 cells.
Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Expression System
Expi293
Species
Human
Tag
N-His/Flag
Form
Lyophilized from sterile distilled Water up to 100 μg/mL
Molecular Mass
65-140 kDa
Protein length
51-183
AA Sequence
QVSHRYPRIQSIKVQFTEYKKEKGFILTSQKEDEIMKVQNNSVIINCDGFYLISLKGYFSQEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSLDDFHVNGGELILIHQNPGEFCVL
Endotoxin
< 1 EU/μg of protein (determined by LAL method)
Purity
> 95% by SDS-PAGE
Applications
Functional Study; SDS-PAGE
Storage
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
SDS-PAGE
Quality Control Testing

SDS-PAGE under reducing condition

Bioactivity-ELISA 1
Result of bioactivity analysis

Data Sheet MSDS
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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