Recombinant Human VCP Protein (2-589), C-His-tagged
Product Description
Cat
IMP-6668
Official Symbol
VCP
Product Overview
Purified recombinant protein of Human valosin containing protein (VCP) with a C-His tag was expressed in E. coli.
Description
This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients.
Expression System
E. coli
Species
Human
Tag
C-His
Form
Supplied as a 0.2 μm filtered solution of 50mM TrisHCl, pH 8.0.
Molecular Mass
66.4 kDa
Protein length
2-589
Endotoxin
< 0.1 ng/μg
Purity
> 95% as determined by SDS-PAGE and Coomassie blue staining
Storage
Store at -80 centigrade.
Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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