Product Overview
Purified recombinant protein of Human c-fos induced growth factor (vascular endothelial growth factor D) (FIGF), Phe89-Arg205, with N-terminal His-Trx tag, expressed in E. coli.
Description
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011]
Form
25mM Tris, pH 8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl