Recombinant Monkey ICOSLG Protein (Asp19-Thr256), C-hFc-tagged

Product Description

Cat

IMP-10423

Official Symbol

ICOSLG

Product Overview

Recombinant Cynomolgus Monkey B7-H2 protein (Asp19-Thr256) with a Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Human embryonic kidney cell.

Description

Enables identical protein binding activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 production. Located in cytoplasmic ribonucleoprotein granule and plasma membrane.

Expression System

HEK293

Species

Monkey

Tag

C-hFc

Predicted N Terminal

Asp19

Form

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Molecular Mass

Predicted Molecular Mass: 53 kDa
SDS-PAGE: 75-87 kDa, reducing conditions

Protein length

Asp19-Thr256

Bio-activity

Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey ICOS Fc Chimera is immobilized at 0.5 μg/mL (100 μL/well), the concentration of Recombinant Cynomolgus Monkey B7-H2 Fc Chimera that produces 50% of the optimal binding response is 4-20 ng/mL.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 500 μg/mL in PBS.

SDS-PAGE

Bioactivity-ELISA 1

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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