Recombinant Monkey ICOSLG Protein (Asp19-Thr256), C-hFc-tagged

Product Description

Cat

IMP-10423

Official Symbol

ICOSLG

Product Overview

Recombinant Cynomolgus Monkey B7-H2 protein (Asp19-Thr256) with a Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Human embryonic kidney cell.

Description

Enables identical protein binding activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 production. Located in cytoplasmic ribonucleoprotein granule and plasma membrane.

Expression System

HEK293

Species

Monkey

Tag

C-hFc

Predicted N Terminal

Asp19

Form

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Molecular Mass

Predicted Molecular Mass: 53 kDa
SDS-PAGE: 75-87 kDa, reducing conditions

Protein length

Asp19-Thr256

Bio-activity

Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey ICOS Fc Chimera is immobilized at 0.5 μg/mL (100 μL/well), the concentration of Recombinant Cynomolgus Monkey B7-H2 Fc Chimera that produces 50% of the optimal binding response is 4-20 ng/mL.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 500 μg/mL in PBS.

SDS-PAGE

Bioactivity-ELISA 1

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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