Recombinant Monkey TNFRSF17 Protein (Met1-Ile54), C-Fc-tagged

Product Description

Cat

IMP-9549

Official Symbol

TNFRSF17

Product Overview

Recombinant Cynomolgus/Rhesus Macaque BCMA (Met1-Ile54) protein with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in human embryonic kidney cell.

Description

BCMA, B cell maturation antigen, also known as Tumor Necrosis Factor Receptor Superfamily member 17 (gene name TNSFR17), is a member of the TNFR superfamily, due to the presence of its TNFR motif.

Expression System

HEK293

Species

Monkey

Tag

C-Fc

Predicted N Terminal

Met1

Form

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Molecular Mass

Predicted Molecular Mass: 33 kDa
SDS-PAGE: 37-43 kDa, reducing conditions

Protein length

Met1-Ile54

Bio-activity

Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. The ED50 for this effect is 30-180 ng/mL.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 500 μg/mL in PBS.

SDS-PAGE

Bioactivity-ELISA 1

Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. The ED50 for this effect is 30-180 ng/mL.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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