Recombinant Monkey TNFRSF17 Protein (Met1-Ile54), C-Fc-tagged

Product Description

Cat

IMP-9549

Official Symbol

TNFRSF17

Product Overview

Recombinant Cynomolgus/Rhesus Macaque BCMA (Met1-Ile54) protein with a human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in human embryonic kidney cell.

Description

BCMA, B cell maturation antigen, also known as Tumor Necrosis Factor Receptor Superfamily member 17 (gene name TNSFR17), is a member of the TNFR superfamily, due to the presence of its TNFR motif.

Expression System

HEK293

Species

Monkey

Tag

C-Fc

Predicted N Terminal

Met1

Form

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Molecular Mass

Predicted Molecular Mass: 33 kDa
SDS-PAGE: 37-43 kDa, reducing conditions

Protein length

Met1-Ile54

Bio-activity

Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. The ED50 for this effect is 30-180 ng/mL.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Notes

Disulfide-linked homodimer

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 500 μg/mL in PBS.

SDS-PAGE

Bioactivity-ELISA 1

Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. The ED50 for this effect is 30-180 ng/mL.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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