Product Overview
Recombinant Mouse BTLA protein, Glu30-Gly176 (Lys173Glu), with a Mouse IgG2A (Glu98-Lys330) tag at C-terminus was expressed in Mouse myeloma cell line.
Description
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
Bio-activity
Measured in a competitive binding assay. When Recombinant Mouse HVEM/TNFRSF14 Fc Chimera is immobilized at 0.1 μg/mL (100 μL/well), Recombinant Mouse BTLA Fc Chimera inhibits 50% binding of biotinylated Recombinant Mouse BTLA Fc Chimera (0.2 μg/mL ) at the concentration range of 0.3-1 μg/mL.
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
