Product Overview
Purified recombinant protein of Mouse CART prepropeptide (cDNA clone MGC: 66635 IMAGE: 6817832), complete cds, with C-terminal Myc/DDK tag, expressed in HEK293T cells.
Description
This gene encodes preproprotein isoforms that are processed into multiple biologically active peptides. Expression of this gene is regulated by cocaine and other drugs, and is associated with feeding/appetite and stress response. Mice lacking the encoded protein are predisposed to obesity. Deficiency of the encoded protein in mice results in pancreatic islet dysfunction, impaired insulin secretion and glucose intolerance. Alternative splicing results in multiple transcript variants encoding different isoforms, which are subsequently processed into mature peptides. [provided by RefSeq, Jul 2015]
Form
25mM Tris.HCl, pH 7.3, 100mM glycine, 10% glycerol