Description
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bio-activity
Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD200 R1 Fc Chimera is immobilized at 1 μg/mL (100 μL/well), the concentration of Recombinant Mouse CD200 that produces 50% of the optimal binding response is 0.25-1.5 μg/mL.
Storage
12 months from date of receipt, ≤ -20 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, ≤ -20 centigrade under sterile conditions after reconstitution.
