Product Overview
Recombinant mouse CD79A (NP_031681.2) (Met1-Arg137) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; Recombinant mouse CD79B (NP_031681.2) (Met1-Asp158) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the mouse CD79A&CD79B heterodimer was purified.
Description
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Form
Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5% mannitol and 0.01% Tween80.
Molecular Mass
The recombinant mouse CD79A&mouse CD79B heterodimer comprises 264 (120+144) amino acids and has a calculated molecular mass of 30.3 (13.8+ 16.5) kDa. The apparent molecular mass of the recombinant protein is approximately 34.6, 28.3 and 24.1 kDa respectively in SDS-PAGE under reducing conditions.
