Recombinant Mouse FCGR2B Protein (Thr30-Arg207), C-10×His-tagged
Product Description
Cat
IMP-9687
Official Symbol
Fcgr2b
Product Overview
Recombinant Mouse Fc gamma RIIB/CD32b protein (Thr30-Arg207) with a C-terminal 10-His tag was expressed in Mouse myeloma cell line.
Description
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Expression System
Mouse myeloma cell line
Species
Mouse
Tag
C-10×His
Predicted N Terminal
Thr30
Form
Lyophilized from a 0.2 μm filtered solution in PBS.
Molecular Mass
Predicted Molecular Mass: 22 kDa
SDS-PAGE: 30-40 kDa, reducing conditions
Protein length
Thr30-Arg207
Bio-activity
Measured by its ability to bind mouse IgG with an estimated KD < 150 nM.
Endotoxin
<0.10 EU/μg of the protein by the LAL method.
Purity
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Notes
Monomer
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution
Reconstitute at 100 μg/mL in sterile PBS.
Data Sheet MSDS
For research or industrial raw materials, not for personal medical use!

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