Recombinant Mouse Fcgr3 Protein (Ala31-Thr215), C-10×His-tagged

Product Description

Cat

IMP-9706

Official Symbol

Fcgr3

Product Overview

Recombinant Mouse Fc gamma RIII/CD16 protein (Ala31-Thr215) with a C-terminal 10-His tag was expressed in Mouse myeloma cell line.

Description

Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; phagocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc fragment of IgG receptor IIa).

Expression System

Mouse myeloma cell line

Species

Mouse

Tag

C-10×His

Predicted N Terminal

Ala31

Form

Supplied as a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 22.5 kDa
SDS-PAGE: 30-45 kDa, reducing conditions

Protein length

Ala31-Thr215

Bio-activity

Measured by its ability to bind mouse IgG with an estimated Kd <15 nM.

Endotoxin

<1.0 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after opening.
3 months, -20 to -70 centigrade under sterile conditions after opening.

Data Sheet MSDS

Datasheet MSDS

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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