Recombinant Mouse Fcgr4 Protein (Gly21-Gln203), C-10×His-tagged

Product Description

Cat

IMP-9707

Official Symbol

Fcgr4

Product Overview

Recombinant Mouse FcgR4/CD16-2 protein (Gly21-Gln203) with a C-terminal 10-His tag was expressed in Mouse myeloma cell line.

Description

Enables IgE receptor activity and IgG receptor activity. Involved in neutrophil activation and positive regulation of bone resorption. Located in cell surface. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); glomerulonephritis (multiple); hematologic cancer (multiple); and immunodeficiency 20. Orthologous to human FCGR3A (Fc fragment of IgG receptor IIIa) and FCGR3B (Fc fragment of IgG receptor IIIb).

Expression System

Mouse myeloma cell line

Species

Mouse

Tag

C-10×His

Predicted N Terminal

Gly21

Form

Lyophilized from a 0.2 μm filtered solution in PBS.

Molecular Mass

Predicted Molecular Mass: 22.3 kDa
SDS-PAGE: 25-35 kDa, reducing conditions

Protein length

Gly21-Gln203

Bio-activity

Measured by its ability to bind mouse IgG with an estimated Kd <1 nM.

Endotoxin

<0.10 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 100 μg/mL in sterile PBS.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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