Recombinant Mouse GAS6 Protein (Asp115-Pro673), C-6×His-tagged

Product Description

Cat

IMP-10142

Official Symbol

GAS6

Product Overview

Recombinant Mouse Gas6 protein (Asp115-Pro673) with a C-terminal 6×His tag was expressed in Mouse myeloma cell line.

Description

This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia.

Expression System

Mouse myeloma cell line

Species

Mouse

Tag

C-6×His

Predicted N Terminal

Asp115

Form

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Molecular Mass

Predicted Molecular Mass: 62 kDa
SDS-PAGE: 72 kDa, reducing conditions

Protein length

Asp115-Pro673

Bio-activity

Measured by its ability to down regulate the expression of Axl in DU145 human prostate carcinoma cells. The ED50 for this effect is 20-100 ng/mL.

Endotoxin

<1.0 EU/μg of the protein by the LAL method.

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.

Reconstitution

Reconstitute at 100 μg/mL in sterile PBS.

Data Sheet MSDS

Datasheet MSDS

For research or industrial raw materials, not for personal medical use!

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